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  Subtle Technologies: Bullet and the Biohack - Animating and Repurposing Dead Organs

Culture of cells onto bio-INcompatible substrates with no relationship to any natural micro-environment.

Talking about the collaborative research conducted at the Pelling Lab for Biophysical Manipulation, Dr Andrew Pelling's presentation showcased his bio-hacking activities that literally pushes limits of biological function. For instance, he showed how his team of PhD's and post-docs are capable of creating microfluidic system that cannot only hold but also bend cells.


Growing of human-jellyfish hybrid ‘skins’ onto LEGO mini-figures.

Developed in preparation for his residency stint at SymbioticA (2011), LEGO project grows living 'skins' around LEGO plastics through a process of culturing genetically modified human cells (including HeLa) expressing fluorescent jellyfish proteins. 

Decellularised process of mouse heart

In a facinating 'Bio-hacking Project', Andrew and his team used a "decellularising" process to remove cells from mouse hearts (otherwise disposed) leaving behind the extracellular matrix (ECM), and then used the heart scaffold to grow liver cells on top, boasting that by "adding a couple of electrodes" you'll have a pumping heart with liver cells.


Multi-bioreactor setup

By using EMC, Andrew's team discovered that they can produce cheap callogen scaffolds, otherwise expensive and difficult to manipulate into natural shapes. Multiple-bioreactor set up is used to collect pure EMC to create designer biodevices. 

Decellularised steak 

Moving from a decellularised steaks, Andrew attested to the hard work his lab before sharing an astonishing result that had emerged on the day of his talk, an image featuring a decelluarised apple with human tissue cells growing on top of it!

 
http://subtletechnologies.com/events/festival-2012/symposium/bull...
 
Other References: C-LAB:blog: Broad Vision: Exhibition Private View
C-LAB:blog: Subtle Technologies: A conversation with Alondra Nelson, Heidi McKenzie and Jeff Thomas
C-LAB:blog: Subtle Technologies: Art from Synthetic Biology / The Sensorial Invisibility of Plants
C-LAB:blog: Subtle Technologies: BIOART - Art from the Laboratory
C-LAB:blog: Subtle Technologies: Broadvision: the art & science of looking
C-LAB:blog: Subtle Technologies: Bullet and the Biohack - Animating and Repurposing Dead Organs
C-LAB:blog: Subtle Technologies: Cc: me
C-LAB:blog: Subtle Technologies: Cellular Performance
C-LAB:blog: Subtle Technologies: Consciousness | Symbiosis State Project
C-LAB:blog: Subtle Technologies: Exploratory soundscapes of arterial flow
C-LAB:blog: Subtle Technologies: Henrietta Lacks in Text and Context
C-LAB:blog: Subtle Technologies: Motion Studies
C-LAB:blog: Subtle Technologies: Poster Exhibition - Common Ground
C-LAB:blog: Subtle Technologies: Primate Cinema: Apes as family
C-LAB:blog: Subtle Technologies: Proposal for resuscitating prehistoric lives
C-LAB:blog: Subtle Technologies: Public dialogue on EXPERIMENTS
C-LAB:blog: Subtle Technologies: Screening of Momentum – Rachel Armstrong
C-LAB:blog: Subtle Technologies: Sensing between the lines
C-LAB:blog: Subtle Technologies: Speed Networking
C-LAB:blog: Subtle Technologies: Using Biology to Inspire Engineering Design
C-LAB:blog: Subtle Technologies: Using MRI and drawing as maps to heal my frozen shoulder
C-LAB:blog: Subtle Technologies: Weak measurements, strong insights, and the double-slit experiment
C-LAB:blog: Subtle Technologies: Workshop - The Physarum Experiments
C-LAB:blog: Subtle Technologies: Youtube: from stick figures to string theory
C-LAB:event: SUBTLE TECHNOLOGIES
 
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